More exciting things to come...
February 6th, 2026
Good news! Our CIN-seq paper was accepted today in Advanced Science. We extended our FUNseq pipeline to a new method, called CIN-seq, which is specifically designed for single-cell multi-omic profiling of chromosomal instability (CIN). Using this method, we identified a previously unrecognized mechanism whereby cells undergoing multipolar mitosis, a CIN phenotype, can survive and successfully progress through mitosis despite genomic abnormalities.
November 27th, 2025
Great news! Our SPARC consortium, led by Alina Rwei, has been awarded an NWO Perspectief grant (€7.2M) to make immunotherapy effective for more cancer patients. More details can be found here!
October 17th, 2025
During our annual Lab Day, we had active discussions and inspiring brainstorming sessions, including reflections on our future research directions. We look forward to the next edition!
October 1st, 2025
We are excited to welcome Swati as our new Project Manager, who will be supporting and coordinating our ongoing research projects!
September 1st, 2025
New students! Kiki and Thomas have joined the lab for their master end projects. Welcome, both!
April 1st, 2025
Welcome back, Johanna van Vliet! It's exciting to have you rejoin us as a PhD student! Looking forward to our fun journey ahead!
March 14th, 2025
A small farewell for Pin-Rui! Wishing you success in your next challenge; you will be greatly missed!
December 16th, 2024
Another great news! Our €3 million NWO-XL Consortium Project has been funded! The project will investigate the role of myeloid cells in the success or failure of immunotherapy, and our spatial FUNseq technology will be applied to gain insights into these processes.
December 11th, 2024
Congratulations to Dr. Pin-Rui Su on successfully defending his PhD thesis! It’s an amazing thesis, and we are extremely proud of him!
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December 3rd, 2024
Fantastic news! Miao was awarded the prestigious ERC Consolidator Grant! She and her team look forward to using it to develop more advanced imaging and sequencing technologies to gain a better understanding of chromosomal instability in gastric cancer!
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Thank you to my group for the beautiful flowers! |
September, 2024
New students! Amke, Wilco and Lulu have joined the lab for their master end projects. Welcome, everyone!
February, 2024
New members! Toba has joined the group for his PhD, and Emilie has joined the lab for her internship. Welcome, Toba and Emile!
September/October/November, 2023
New members! Sjoukje, Johanna and Jorrit have joined the lab for their master end projects. Lars and Junfeng have joined the group for their PhDs. Welcome, everyone!
August 11th, 2023
Our 'Fast and Accurate Cell Tracking: a real-time cell segmentation and tracking algorithm to instantly export quantifiable cellular characteristics from large scale image data' paper was accepted today in Cell Reports Methods. FACT combines fast GPU-based GTWeka cell segmentation with real-time Gaussian mixture model-based cell linking to enable instant processing of large scale image data within minutes after image acquisition.
August 10th, 2023
Our 'Spatial Transcriptomic Technologies' Review (DOI: https://doi.org/10.3390/cells12162042) was published online today. Check it out to see an overview of current spatial transcriptomic technologies including our spatially annotated FUNseq.
July 21st, 2023
Our 'Protocol for profiling in vitro intratumor heterogeneity using spatially annotated single-cell sequencing' (DOI: 10.1016/j.xpro.2023.102447) was published online today. Check it out to see how you can spatially profile single cells using our spatially annotated FUNseq.
July 20th, 2023
Great news! Our collaborative EMC2 Research Synergy Project (with Drs. Wakkee, Zandwijk-Hollestein, Balcioglu and Mooyaat) has been granted! In this project, we aim to identify metastatic cutaneous squamous cell carcinomas (cSCC) cells and the role of tumor microenvironment in cSCC metastasis.
December 20th, 2022
Excellent news! Our collaborative KWF TKI project with SkylineDx has been granted! In this project, we aim to identify predictive signatures of metastasis and druggable targets in head and neck squamous cell carcinoma. (also check out the Oncode news)
December 1st, 2022
Piera has joined our group as a technician. Welcome, Piera!
October 5th, 2022
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Great news! Our team has won the Computable Award 2022 (the Digital Transformation category). Check here for all the final winners.
Nomination information: Together with our collaborator, our team has developed software and a smart microscope to detect and isolate aggressive subpopulations of cancer cells and to determine the RNA sequence of those cells. As a result, potential new drugs for cancer may also come into the picture in the future. This is the reason for the jury of the Computable Awards 2022 to nominate our team in the Digital Transformation category. Please check our 2022 Nature Biomedical Engineering paper for more details.
Nomination information: Together with our collaborator, our team has developed software and a smart microscope to detect and isolate aggressive subpopulations of cancer cells and to determine the RNA sequence of those cells. As a result, potential new drugs for cancer may also come into the picture in the future. This is the reason for the jury of the Computable Awards 2022 to nominate our team in the Digital Transformation category. Please check our 2022 Nature Biomedical Engineering paper for more details.
August 29th, 2022
Tsai-Ying Chen and Chi-Hung Hung have joined our group for their PhDs! Welcome, both!
July 1st, 2022
Excellent news!! Miao was awarded a NWO VIDI grant!
July 1st, 2022
Good news! Our team has been nominated for the Computable Awards 2022 (link)!
June 17th, 2022
June 13th, 2022
Our functional single cell proteomic profiling (FUNpro) paper was published online today (https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(22)00106-0)! Check it out to see how we combined functional single cell selection with single cell proteomic profiling to reveal heterogeneity in DNA damage response dynamics.
March 17th, 2022
Our functional single cell sequencing (FUNseq) paper was published online today, which has been highlighted in a number of media outlets:
https://www.sciencedaily.com/releases/2022/03/220317120354.htm
https://www.genengnews.com/topics/cancer/sequencing-aggressive-cells-identifies-targets-in-heterogenous-cancers-expeditiously/
https://www.trouw.nl/zorg/nieuwe-methode-van-erasmus-mc-en-tu-delft-weet-agressieve-kankercellen-op-te-sporen~b36592e9/
https://amazingerasmusmc.nl/biomedisch/agressieve-kankercel-in-de-spotlight/
https://www.sciencedaily.com/releases/2022/03/220317120354.htm
https://www.genengnews.com/topics/cancer/sequencing-aggressive-cells-identifies-targets-in-heterogenous-cancers-expeditiously/
https://www.trouw.nl/zorg/nieuwe-methode-van-erasmus-mc-en-tu-delft-weet-agressieve-kankercellen-op-te-sporen~b36592e9/
https://amazingerasmusmc.nl/biomedisch/agressieve-kankercel-in-de-spotlight/
February 15th, 2022
Phuong Nguyen joined our group for her bachelor end project. Welcome, Phuong!
February, 2022
Silvia Andaloro, Rafael Geldof and Jeske Strik joined our group for their master internship or end project. Welcome, all!
January 21st, 2022
Congrats! Myrthe's paper just got accepted in Frontiers in Bioengineering and Biotechnology (invited submission)!
January 19th, 2022
Congrats! Miao was selected as one of the winners of InspiringFifty Deep Tech 2021 Award!
December 6th, 2021
Jasmin Singh joined our group for her master internship. Welcome, Jasmin!
September 6th, 2021
Sabine de Klein and Alexander Neutel joined our group for their bachelor end projects. Welcome, Sabine and Alexander!
May 10th, 2021
Bo-Yi Lin joined our group for his bachelor end project. Welcome, Bo-Yi!
April 23rd, 2021
Congrats! Our group's first manuscript about the FUNseq technology has been accepted at Nature Biomedical Engineering!
March 5th, 2021
We started UFO Biosciences, a facility at Erasmus MC and Oncode Institute to make our fSCS/FUNseq technology available to everyone who is interested! Our microscopy-based cell subtyping allows differentiation of cell subtypes in heterogeneous populations, like tumor samples, and linking of distinguishing phenotypes to underlying genotypes. Check it out!
March 2nd, 2021
Great news! Miao is invited to give a talk at the Oxford Global Genomic Technologies Workshop, June 6-9, 2021.
February, 2021
Myrthe Smit and David Garcia van Bijsterveld joined our group for their master end project and internship. Welcome, Myrthe and David!
December, 2020
Esther Hoogerwerf, Lianne Trap, Myrrhe Venema and Esther de Vries joined our group for their master internships. Welcome, Esther (Hoogerwerf), Lianne, Myrrhe and Esther (de Vries)!
November, 2020
Great news! Miao is invited as a plenary speaker in the following conferences:
- 2020/11/03 - 2020/11/05: Oxford Global NextGen Omics Series UK (Single Cell Analysis Congress)
- 2020/11/19 - 2020/11/20: VIB Emerging Technologies in Single Cell Research
- 2020/11/03 - 2020/11/05: Oxford Global NextGen Omics Series UK (Single Cell Analysis Congress)
- 2020/11/19 - 2020/11/20: VIB Emerging Technologies in Single Cell Research
October 15th, 2020
Great news! Our group received another Technology Development Fund from Oncode to validate fSCS-related technologies for commercial application!
June 15th, 2020
Great news! Our group received two small grants from CGC.nl in collaboration with Lenstra's group at NKI and Ritsma's group at Leiden UMC!
February 11th, 2020
Great news! Eight PIs (including Miao) from our department won the 2020 Ammodo Science Award for groundbreaking research!
February-March, 2020
Francesca Kessler, Oussama Akhiyat and Ivy Liang joined our group for their bachelor end projects! Welcome, Francesca, Oussama and Ivy!
December 15th, 2019
Great news! Our group and Joana Gonçalves's group (TU Delft) have received a grant funded by the Convergence Initiative for Health and Technology, promoted by the Erasmus MC and the TU Delft. We are hiring two 2-year postdocs for this project. If you are interested, please apply at this link!
November 18th, 2019
Great news! Our group received a grant from the Oncode Technology Development Fund, which will be used to build our UFO2! Thanks, Oncode!
November 15th, 2019
Kate Feller joined our group as a PhD student! Welcome, Kate!
October-November, 2019
Yasin Begce, Antoine Rolland and Roos Kraaijveld joined our group for their bachelor end projects! Welcome, Yasin, Antoine and Roos!
September 2nd, 2019
Yassin El Yahyaoui joined our group for his master end project! Welcome, Yassin!
August 5th, 2019
Ting-Chun (Jason) Chou joined our group as a PhD student! Welcome, Jason!
June 1st, 2019
Jelle Storteboom joined our group as a postdoctoral fellow! Welcome, Jelle!
April 1st, 2019
Reza Ghadiri Rad joined our group as a PhD student! Welcome, Reza!
February 11th, 2019
Eva van Oosten (NanoBiology program) joined our group for her bachelor end project! Welcome, Eva!
January 11th, 2019
Great news!! Our group won the best group booth award during the annual Oncode/CGC meeting! This is awarded based on creativity, effort and clear explanation of the research. Thank you, Max, Debby and Pin-Rui, for your great job on this!!
November 26th, 2018
Great news!! Miao is selected for an Oncode investigator position! Thanks for everyone in the group for their hard work to make this possible. This will help us do great research in years to come!
October 22nd, 2018
Debby van Steenderen from Leiden University joined our group for her master end project! Welcome, Debby!
October 1st, 2018
Max Betjes (NanoBiology program) joined our group for his master end project! Welcome, Max! Let's get some lineage straight!
October 1st, 2018
Li You, a computational scientist, joined our group as a postdoc! Welcome, Li!
September 21st, 2018
Great news!! Miao received the Erasmus MC fellowship. It will be officially awarded at the annual Erasmus public lecture at De Doelen. See the link here!
September 14th, 2018
Pin-Rui (Ray) Su joined our group for his PhD study! Welcome, Pin-Rui!
August 13th, 2018
Felix Leufkens (NanoBiology program) joined our group for his bachelor end project! Welcome, Felix!
August 31st, 2018
Congrats to Ankush for his new researcher position at University of Oslo in Norway! We will miss you...
July 20th, 2018
Great news! We received a Dragon Gate Project grant, a project funded by Taiwan Ministry of Science & Technology in collaboration with Dr. Cheng-Chih Hsu's at National Taiwan University.
July 15th, 2018
Congrats to Lois Van der Drift and Lotte Mulder for completing their master internship and bachelor end project in our group. Well done!
May 3rd, 2018
Great news! We have been awarded an Erasmus Mrace grant!
April 24th, 2018
Great news! Miao is awarded the CGC Young PI grant! We will use the money for an exciting new project in collaboration with Dr. Alexander van Oudenaarden.
February 16th, 2018
Our Mira 900 Ti:Sapph system for two-photon imaging is up and running today!
February 15th, 2018
Lois Van der Drift and Lotte Mulder, two students from the Nanobiology program, joined our group for their master internship and bachelor end project, respectively. Welcome!
December 6th, 2017
Miao is invited to share her experience on receiving the Veni award at the CHAINS conference!
October 1st, 2017
Paulina Gąsecka, a joint postdoc in our group and Dr. Brinks' lab, officially started today! Welcome, Paulina!
September 21st, 2017
Our lab renovation was completed yesterday!! We officially moved in to the new lab today!
July 26th, 2017
Great news!! Miao is awarded the NWO-VENI grant!
June, 2017
Our collaborator, Dr. Daan Brinks, started his lab at TU Delft!
June, 2017
Miao officially joined the Erasmus University Medical Center, Rotterdam in June and also became a new PI in the Cancer GenomiCs.nl consortium (CGC)!!
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